发文献得奖励 特价促销,"奖"享不断
Recombinant Human CD38 (C-Fc)
Catalog# BDAF0002
Product information
| 产品货号 | BDAF0002 |
| 别名 | ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase;CD38;T10 |
| 产品名称 | Recombinant Human CD38 (C-Fc) |
| 类别 | 重组蛋白 |
| 推荐应用 | Dependent by end user |
| 存储缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
| Human Swissprot No. | P28907 |
| 参考分子量 | 70-90kDa, reducing conditions |
| 预测分子量 | 132kDa |
| 运输及保存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 表达系统 | human cells |
| 内毒素 | Less than 0.1 ng/µg (0 EU/µg) as determined by LAL test. |
| 宿主 | human cells |
| 背景介绍 | CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells. |