发文献得奖励 特价促销,"奖"享不断
Recombinant Human CD47 (C-Fc)
Catalog# BDAF0014
Product information
| 产品货号 | BDAF0014 |
| 别名 | Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6 |
| 产品名称 | Recombinant Human CD47 (C-Fc) |
| 类别 | 重组蛋白 |
| 推荐应用 | Dependent by end user |
| 存储缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
| Human Swissprot No. | Q08722 |
| 参考分子量 | 60kDa, reducing conditions |
| 预测分子量 | 99.2kDa |
| 运输及保存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 表达系统 | human cells |
| 内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 宿主 | human cells |
| 背景介绍 | CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes. |