产品基本信息

• 产品货号 RM9211
• 别名 GTPase KRas;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;
• 产品名称 K-Ras (2R11) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 KRAS
• 蛋白名称 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 3845
• Human Swissprot No. P01116
• Mouse Gene ID 16653
• Mouse Swissprot No. P32883
• Rat Swissprot No. P08644
• 特异性 Endogenous
• 稀释度 IHC-P 1:100-1:500, WB 1:2000-1:10000, IF 1:200-1:1000, ELISA 1:5000-1:20000
• 参考分子量 22kDa
• 预测分子量 22kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],
• 细胞定位 Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endomembrane system . Cytoplasm, cytosol .; [Isoform 2B]: Cell membrane ; Lipid-anchor .

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