产品基本信息

• 产品货号 RM7389
• Uniprot ID Q9EPK8,Q9ERZ8
• Gene ID 63873,66026
• 别名 Trp12; VRL-2; VROAC; OTRPC4; VR-OAC; 0610033B08Rik
• 产品名称 TRPV4 (8L13) Rabbit Monoclonal Antibody
• 类别 抗体产品
• Clonality Monoclonal
• 推荐应用 IHC-P,IF-P
• 反应种属 Mouse,Rat
• 存储缓冲液 Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% New type preservative N and 0.05% BSA.
• 免疫原 A synthetic peptide of mouse TRPV4
• 稀释度 IHC-P/IF-P 1:200-1:500
• 预测分子量 53kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 IgG
• 背景介绍 Enables several functions, including SH2 domain binding activity; calcium channel activity; and osmosensor activity. Involved in several processes, including cellular response to osmotic stress; positive regulation of MAPK cascade; and positive regulation of cytokine production. Acts upstream of or within hyperosmotic salinity response; regulation of response to osmotic stress; and vasopressin secretion. Located in adherens junction and cilium. Is active in plasma membrane. Is expressed in several structures, including brain; limb; respiratory system; sensory organ; and skeleton. Used to study autosomal dominant nonsyndromic deafness 25. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2C; motor neuron disease (multiple); osteochondrodysplasia (multiple); and osteonecrosis. Orthologous to human TRPV4 (transient receptor potential cation channel subfamily V member 4). [provided by Alliance of Genome Resources, Apr 2025]
• 纯化 Affinity Purification

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产品详情