产品基本信息

• 产品货号 RM7390
• Uniprot ID Q9HBE5
• Gene ID 50615
• 别名 NILR; CD360; IMD56;IL21R;IL 21R
• 产品名称 IL-21R (5M13) Rabbit Monoclonal Antibody
• 类别 抗体产品
• Clonality Monoclonal
• 推荐应用 FCM
• 反应种属 Human
• 存储缓冲液 Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% New type preservative N and 0.05% BSA.
• 免疫原 Recombinant protein of human IL-21R
• 稀释度 FCM 1:200-1:500
• 预测分子量 59kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 IgG
• 背景介绍 The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
• 纯化 Affinity Purification

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产品详情