Axl (6Y9) Rabbit Monoclonal Antibody
产品基本信息
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产品货号
RM7432
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Uniprot ID
P30530
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Gene ID
558
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别名
ARK; UFO; AXL3; JTK11; Tyro7
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产品名称
Axl (6Y9) Rabbit Monoclonal Antibody
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类别
抗体产品
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Clonality
Monoclonal
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推荐应用
WB,IF-ICC,FCM
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反应种属
Human
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存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% New type preservative N and 0.05% BSA.
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免疫原
Recombinant protein of human Axl
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稀释度
WB 1:1000, IF-ICC 1:100, FCM 1:200-1:500
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参考分子量
138kDa
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预测分子量
98kDa
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运输及保存条件
-20°C/1 year
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宿主
Rabbit
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同种型
IgG
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背景介绍
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]
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纯化
Affinity Purification
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