产品基本信息

• 产品货号 RM8760
• 别名 KIAA2016 STEF
• 产品名称 TIAM2 (4A8) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 TIAM2,KIAA2016,STEF
• 蛋白名称 Rho guanine nucleotide exchange factor TIAM2 (SIF and TIAM1-like exchange factor) (T-lymphoma invasion and metastasis-inducing protein 2) (TIAM-2)
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-ICC,FCM
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 26230
• Human Swissprot No. Q8IVF5
• Mouse Gene ID 24001 
• Mouse Swissprot No. Q6ZPF3
• 特异性 Endogenous
• 稀释度 IHC-P 1:200-1:1000, WB 1:1000-1:5000, IF-ICC1:200-1:1000, FCM 1:100-1:500
• 参考分子量 187kDa
• 预测分子量 187kDa
• 运输及保存条件 -20°C/1 year(Do not lower than -25°C)
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
• 细胞定位 SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q6ZPF3}. Perikaryon {ECO:0000250|UniProtKB:Q6ZPF3}.
• 纯化 Protein A

图片

Western Blot analysis using K562  lysates,primary antibody was diluted at 1:1000, 4°over night, Dylight 800 secondary antibody was diluted at 1:10000, 37° 1hour.

产品详情