产品基本信息

• 产品货号 RM8768
• 产品名称 PDE1B (12T15) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 PDE1B PDE1B1 PDES1B
• 蛋白名称 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (63 kDa Cam-PDE)
• Clonality Monoclonal
• 推荐应用 WB,IHC-P
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 5153
• Human Swissprot No. Q01064
• Mouse Swissprot No. Q01065
• Rat Swissprot No. Q01066
• 特异性 Endogenous
• 稀释度 IHC-P 1:200-1:1000, WB 1:1000-1:5000
• 参考分子量 59kDa
• 预测分子量 59kDa
• 运输及保存条件 -20°C/1 year(Do not lower than -25°C)
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
• 细胞定位 Cytoplasm, cytosol .
• 纯化 Protein A

图片

Western Blot analysis using HeLa  lysates,primary antibody was diluted at 1:1000, 4°over night, Dylight 800 secondary antibody was diluted at 1:10000, 37° 1hour.

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