Glypican 3 (16C5) Rabbit Monoclonal Antibody
产品基本信息
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产品货号
RM7451
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Uniprot ID
P51654
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Gene ID
2719
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别名
SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2
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产品名称
Glypican 3 (16C5) Rabbit Monoclonal Antibody
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类别
抗体产品
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,IF-P,IF-ICC,FCM
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反应种属
Human
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存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% New type preservative N and 0.05% BSA.
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免疫原
A synthetic peptide of human Glypican 3
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稀释度
WB 1:1000 , IHC-P/IF-P 1:100-1:200 , IF-ICC 1:200-1:500 , FCM 1:100
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参考分子量
66kDa
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预测分子量
66kDa
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运输及保存条件
-20°C/1 year
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宿主
Rabbit
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同种型
IgG
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背景介绍
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
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纯化
Affinity Purification
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