ALAS1 (19J5) Rabbit Monoclonal Antibody
产品基本信息
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产品货号
RM7456
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Uniprot ID
P13196
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Gene ID
211
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别名
ALAS; MIG4; ALAS3; ALASH; ALAS-H
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产品名称
ALAS1 (19J5) Rabbit Monoclonal Antibody
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类别
抗体产品
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,IF-P
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反应种属
Human
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存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% New type preservative N and 0.05% BSA.
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免疫原
A synthetic peptide of human ALAS1
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稀释度
WB 1:1000-1:5000 , IHC-P/IF-P 1:200-1:500
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参考分子量
71kDa
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预测分子量
71kDa
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运输及保存条件
-20°C/1 year
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宿主
Rabbit
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同种型
IgG
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背景介绍
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
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纯化
Affinity Purification
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