产品基本信息

• 产品货号 RM9416
• 产品名称 Cathepsin S (9G11) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 CTSS
• 蛋白名称 Cathepsin S (EC 3.4.22.27)
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 1520
• Human Swissprot No. P25774
• Mouse Swissprot No. O70370
• Rat Swissprot No. Q02765
• 特异性 Endogenous
• 稀释度 IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;
• 参考分子量 25kDa
• 预测分子量 38kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010],
• 组织表达 Alveolar macrophage,Pancreas,Testis,
• 细胞定位 Lysosome . Secreted . Cytoplasmic vesicle, phagosome .
• 功能 Catalytic activity:Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.,Function:Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.,similarity:Belongs to the peptidase C1 family.,subunit:Monomer.,

图片

Immunohistochemical analysis of paraffin-embedded Human kidney

产品详情