产品基本信息

• 产品货号 RM9781
• 别名 SLC3A2;MDU1;4F2 cell-surface antigen heavy chain;4F2hc;4F2 heavy chain antigen;Lymphocyte activation antigen 4F2 large subunit;CD98
• 产品名称 CD98 (1T9) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 SLC3A2
• 蛋白名称 4F2 cell-surface antigen heavy chain
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
• 反应种属 Human
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 6520
• Human Swissprot No. P08195
• Mouse Gene ID 17254
• Mouse Swissprot No. P10852
• Rat Gene ID 50567
• Rat Swissprot No. Q794F9
• 特异性 Endogenous
• 稀释度 IHC-P 1:200-1:1000;WB 1:500-1:2000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200
• 参考分子量 68kDa
• 预测分子量 68kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 This gene is a member of the solute carrier family and encodes a cell surface , transmembrane protein. The protein exists as the heavy chain of a heterodimer , covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants , encoding different isoforms , have been characterized. [provided by RefSeq , Nov 2010] ,
• 细胞定位 Apical cell membrane . Cell membrane ; Single-pass type II membrane protein . Cell junction . Lysosome membrane . Melanosome . Localized at the plasma membrane when associated with SLC7A5/LAT1 or SLC7A8/LAT2 (PubMed:9751058 , PubMed:11311135) . Localized to the apical membrane of placental syncytiotrophoblastic cells (PubMed:11742812) . Recruited to lysosomes by LAPTM4B (PubMed:25998567) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Located selectively at cell-cell adhesion sites (By similarity) . Colocalized with SLC7A8/LAT2 at the basolateral membrane of kidney proximal tubules and small intestine epithelia. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells (By similarity) . .
• 纯化 Recombinant Antibody  expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.

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