产品基本信息

• 产品货号 RM9784
• 别名 Myosin-11;Myosin heavy chain 11;Myosin heavy chain,smooth muscle isoform;SMMHC;KIAA0866
• 产品名称 Myosin Heavy Chain, Smooth Muscle (SMMHC) (19J1) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 MYH11
• 蛋白名称 Myosin Heavy Chain, Smooth Muscle
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 4629
• Human Swissprot No. P35749
• Mouse Swissprot No. O08638
• Rat Swissprot No. Q63862
• 特异性 Endogenous
• 稀释度 IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000
• 参考分子量 255kDa
• 预测分子量 227kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein , converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene , and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv (16) (p13q22) ] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alter
• 细胞定位 Cytoplasmic
• 纯化 Recombinant Antibody  expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.

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