产品基本信息

• 产品货号 RM9813
• 别名 XRCC5;G22P2;X-ray repair cross-complementing protein 5;86 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 2;ATP-dependent DNA helicase II 80 kDa subunit;CTC box-binding factor 85 kDa subunit;CTC85;CTCBF;DNA repair pr
• 产品名称 Ku-80 (8B17) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 XRCC5
• 蛋白名称 X-ray repair cross-complementing protein 5
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 7520
• Human Swissprot No. P13010
• Mouse Gene ID 22596
• Mouse Swissprot No. P27641
• 特异性 Endogenous
• 稀释度 IHC-P 1:1000-1:2000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200
• 参考分子量 83kDa
• 预测分子量 83kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase , and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6 , a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq , Jul 2008] ,
• 细胞定位 Nucleus . Nucleus , nucleolus . Chromosome .
• 纯化 Recombinant Antibody  expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.

图片

产品详情