产品基本信息

• 产品货号 RM9815
• 别名 IKBKE;IKKE;IKKI;KIAA0151;Inhibitor of nuclear factor kappa-B kinase subunit epsilon;I-kappa-B kinase epsilon;IKK-E;IKK-epsilon;IkBKE;Inducible I kappa-B kinase;IKK-i
• 产品名称 IKKε (10T15) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 IKBKE
• 蛋白名称 Inhibitor of nuclear factor kappa-B kinase subunit epsilon
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID 9641
• Human Swissprot No. Q14164
• 特异性 Endogenous
• 稀释度 IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000
• 参考分子量 81kDa
• 预测分子量 81kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG,Kappa
• 背景介绍 IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al. , 2009 [PubMed 19481526]) .[supplied by OMIM , Oct 2009] ,
• 细胞定位 Cytoplasm . Nucleus. Nucleus , PML body . Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent (PubMed:20188669) . Located diffusely throughout the cytoplasm but locates to punctate cytoplasmic bodies when coexpressed with TRIM6 (PubMed:24882218) . .
• 纯化 Recombinant Antibody  expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.

图片

产品详情