产品基本信息
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产品货号
BD-PA0058
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纯度
crude ascites
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别名
DKIR; C3IP1; FLJ27152; KLHL12
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产品名称
KLHL12 Mouse Monoclonal Antibody
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类别
抗体产品
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基因名称
KLHL12
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Clonality
Monoclonal
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推荐应用
WB,Elisa
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反应种属
Human
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存储缓冲液
Ascitic fluid containing 0.03% New type preservative N.
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Human Gene ID
59349
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免疫原
Purified recombinant fragment of human KLHL12 expressed in E. Coli.
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稀释度
WB 1:500-1:2000, ELISA 1:10000
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参考分子量
63kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
2G2
图片
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Western blot analysis using KLHL12 mouse mAb against Hela (1) cell lysate. |
产品详情
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.