产品基本信息

• 产品货号 RM5049
• 别名 Krueppel-like factor 4; KLF4; EZF; GKLF;
• 产品名称 KLF4 (11U14) Rabbit Monoclonal Antibody
• 类别 抗体产品
• 基因名称 KLF4
• 蛋白名称 EZF, GKLF
• Clonality Monoclonal
• 推荐应用 WB,IHC-P,IF-P,IF-ICC,FCM,IP
• 反应种属 Human
• 存储缓冲液 Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
• Human Gene ID 9314
• Human Swissprot No. O43474
• 免疫原 Recombinant protein of human KLF4
• 稀释度 WB 1:1000, IHC-P/IF-P 1:200-1:2000, IF-ICC 1:100, FCM 1:20-1:50, IP 1:20-1:50
• 参考分子量 54kDa
• 预测分子量 54kDa
• 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主 Rabbit
• 同种型 IgG
• 注意事项 KLF4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
• 细胞定位 Nucleus.
• 功能 Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
• 纯度 Affinity-chromatography

图片

	Western blot analysis of KLF4 expression in (1) HeLa cell lysate; (2) NIH/3T3 cell lysate; (3) C6 cell lysate.
	Western blot analysis of extracts from NCCIT cells using RM5049 at 1:1000.

产品详情