产品基本信息
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产品货号
RM6061
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别名
Cone rod homeobox; CORD 2; CRD; CRX; LCA7; OTX3;
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产品名称
CRX (13O19) Rabbit Monoclonal Antibody
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类别
抗体产品
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基因名称
CRX
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蛋白名称
CORD2
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,IF-P
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反应种属
Human
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存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
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Human Gene ID
1406
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Human Swissprot No.
O43186
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免疫原
A synthetic peptide of human CORD2
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稀释度
WB 1:1000-1:5000, IHC-P/IF-P 1:200-1:500
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参考分子量
38kDa
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预测分子量
32kDa
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运输及保存条件
Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
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宿主
Rabbit
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同种型
IgG
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注意事项
CRX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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组织表达
Retina.
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细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
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功能
Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
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纯度
Affinity-chromatography
图片
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Western blot analysis of CRX expression in Y79 cell lysate. |
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Western blot analysis of extracts from Y-79 cells using RM6061 at 1:1000. |
产品详情
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.