CRX (13O19) Rabbit Monoclonal Antibody

货号: RM6061
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规格 价格 货期 数量
  • 50μl
    1200.00
    1个工作日
    100μl
    2200.00
    1个工作日

产品基本信息

  • 产品货号 RM6061
  • 别名 Cone rod homeobox; CORD 2; CRD; CRX; LCA7; OTX3;
  • 产品名称 CRX (13O19) Rabbit Monoclonal Antibody
  • 类别 抗体产品
  • 基因名称 CRX
  • 蛋白名称 CORD2
  • Clonality Monoclonal
  • 推荐应用 WB,IHC-P,IF-P
  • 反应种属 Human
  • 存储缓冲液 Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID 1406
  • Human Swissprot No. O43186
  • 免疫原 A synthetic peptide of human CORD2
  • 稀释度 WB 1:1000-1:5000, IHC-P/IF-P 1:200-1:500
  • 参考分子量 38kDa
  • 预测分子量 32kDa
  • 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
  • 宿主 Rabbit
  • 同种型 IgG
  • 注意事项 CRX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 组织表达 Retina.
  • 细胞定位 Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
  • 功能 Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
  • 纯度 Affinity-chromatography

图片

Western blot analysis of CRX expression in Y79 cell lysate.
Western blot analysis of extracts from Y-79 cells using RM6061 at 1:1000.

产品详情

Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.

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